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The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus
The major histocompatibility complex (MHC) class II transactivator gene (CIITA) encodes an important transcription factor required for HLA class II MHC-restricted antigen presentation. MHC genes, including the HLA class II DRB1*03:01 allele, are strongly associated with systemic lupus erythematosus...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387803/ https://ncbi.nlm.nih.gov/pubmed/21614020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2011.36 |
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