Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are encoded by four genes (HCN1–4) and, through activation by cyclic AMP (cAMP), represent a point of convergence for several psychosis risk genes. On the basis of positive preliminary data, we sought to test whether genetic variatio...

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Autori principali: McIntosh, Andrew M., Simen, Arthur A., Evans, Kathryn L., Hall, Jeremy, MacIntyre, Donald J., Blackwood, Douglas, Morris, Andrew D., Smith, Blair H., Dominiczak, Anna, Porteous, David, Deary, hb Ian J., Thomson, Pippa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2012
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387669/
https://ncbi.nlm.nih.gov/pubmed/22783272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00116
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