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Pre-mRNA splicing by complementation with purified human U1, U2, U4/U6 and U5 snRNPs.
The four major nucleoplasmic small nuclear ribonucleoprotein particles U1, U2, U4/U6 and U5 can be extensively purified from HeLa cells by immunoaffinity chromatography using a monoclonal anti-trimethylguanosine antibody. The snRNP particles in active splicing extracts are selectively bound to the i...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1988
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.20.9415 |
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