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PPARγ is a major driver of the accumulation and phenotype of adipose-tissue T(reg) cells

Obesity and type-2 diabetes (T2D) have increased dramatically over the past several decades, in parallel. One of the major links between these two disorders is chronic, low-grade inflammation (1). Prolonged nutrient excess promotes the accumulation and activation of leukocytes in visceral adipose ti...

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Hlavní autoři: Cipolletta, Daniela, Feuerer, Markus, Li, Amy, Kamei, Nozomu, Lee, Jongsoon, Shoelson, Steven E., Benoist, Christophe, Mathis, Diane
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387339/
https://ncbi.nlm.nih.gov/pubmed/22722857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11132
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