טוען...
S-Farnesyl-Thiopropionic Acid Triazoles as Potent Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase
[Image: see text] We report the design and synthesis of novel FTPA-triazole compounds as potent inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt), through a focus on thioether and isoprenoid mimetics. These mimetics were coupled utilizing a copper-assisted cycloaddition to assemble t...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American
Chemical Society
2011
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387282/ https://ncbi.nlm.nih.gov/pubmed/22754607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200106d |
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