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Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

Regulation of actin dynamics is key to many cell physiological processes, ranging from protrusion formation and control of cell shape to cellular motility, endocytosis, and vesicle movement. The actin-related protein (ARP)2/3 complex is a major actin nucleator organizing branched filament networks i...

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Hlavní autoři: Maritzen, Tanja, Zech, Tobias, Schmidt, Michael R., Krause, Eberhard, Machesky, Laura M., Haucke, Volker
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387086/
https://ncbi.nlm.nih.gov/pubmed/22689987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206468109
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