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Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes

Whereas lysosome-related organelles (LRO) of specialized cells display both exocytic and endocytic features, lysosomes in nonspecialized cells can also acquire the property to fuse with the plasma membrane upon an acute rise in cytosolic calcium. Here, we characterize this unconventional secretory p...

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Main Authors: Laulagnier, Karine, Schieber, Nicole L., Maritzen, Tanja, Haucke, Volker, Parton, Robert G., Gruenberg, Jean
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113771/
https://ncbi.nlm.nih.gov/pubmed/21525240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0193
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