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Engineering Yarrowia lipolytica to Produce Glycoproteins Homogeneously Modified with the Universal Man(3)GlcNAc(2) N-Glycan Core
Yarrowia lipolytica is a dimorphic yeast that efficiently secretes various heterologous proteins and is classified as “generally recognized as safe.” Therefore, it is an attractive protein production host. However, yeasts modify glycoproteins with non-human high mannose-type N-glycans. These structu...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386995/ https://ncbi.nlm.nih.gov/pubmed/22768188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039976 |
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