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Huntingtin Fragments and SOD1 Mutants Form Soluble Oligomers in the Cell
Diffusion coefficients of huntingtin (Htt) fragments and SOD1 mutants expressed in cells were measured using fluorescence correlation spectroscopy. The diffusion mobilities of both non-pathological Htt fragments (25 polyQs) and pathological Htt fragments (103 polyQs) were much slower than expected f...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386994/ https://ncbi.nlm.nih.gov/pubmed/22768276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040329 |
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