Δ(9)-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory

RATIONALE: Cannabis users display a constellation of withdrawal symptoms upon drug discontinuation, including sleep disturbances, irritability, and possibly memory deficits. In cannabinoid-dependent rodents, the CB(1) antagonist rimona-bant precipitates somatic withdrawal and enhances forskolin-stim...

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Bibliographische Detailangaben
Hauptverfasser: Wise, Laura E., Varvel, Stephen A., Selley, Dana E., Wiebelhaus, Jason M., Long, Kelly A., Middleton, Lisa S., Sim-Selley, Laura J., Lichtman, Aron H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386852/
https://ncbi.nlm.nih.gov/pubmed/21559804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2305-5
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