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A screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie

Mammalian cancers depend on ‘multiple hits’, some of which promote growth, and some of which block apoptosis. We screened for mutations that require a synergistic block in apoptosis to promote tissue overgrowth, and identified myopic, the Drosophila homolog of the candidate tumor-suppressor and endo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gilbert, M. Melissa, Tipping, Marla, Veraksa, Alexey, Moberg, Kenneth H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386645/
https://ncbi.nlm.nih.gov/pubmed/21571226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.04.012
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