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A screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie
Mammalian cancers depend on ‘multiple hits’, some of which promote growth, and some of which block apoptosis. We screened for mutations that require a synergistic block in apoptosis to promote tissue overgrowth, and identified myopic, the Drosophila homolog of the candidate tumor-suppressor and endo...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386645/ https://ncbi.nlm.nih.gov/pubmed/21571226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.04.012 |
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