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An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbate diabetes
Maintenance of lymphoid homeostasis in a number of immunological and inflammatory contexts is served by a variety of regulatory T (Treg) cell subtypes, and depends on interaction of the transcription factor Foxp3 with specific transcriptional cofactors. We report that a commonly used insertional mut...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386606/ https://ncbi.nlm.nih.gov/pubmed/22579475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.04.007 |
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