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TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) DEFICIENCY LEADS TO LETHAL PARTIAL HEPATIC ISCHEMIA AND REPERFUSION INJURY
Hepatic ischemia and reperfusion injury (IRI) remains an important challenge in clinical orthotopic liver transplantation (OLT). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the major endogenous regulator of matrix metalloproteinase-9 (MMP-9). In this study, we investigated the functional sig...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386467/ https://ncbi.nlm.nih.gov/pubmed/22407827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25710 |
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