Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate FOXO1 and Genes under Its Transcriptional Regulation

Parkinson disease (PD) is a complex neurodegenerative disorder with largely unknown genetic mechanisms. While the degeneration of dopaminergic neurons in PD mainly takes place in the substantia nigra pars compacta (SN) region, other brain areas, including the prefrontal cortex, develop Lewy bodies,...

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Main Authors: Dumitriu, Alexandra, Latourelle, Jeanne C., Hadzi, Tiffany C., Pankratz, Nathan, Garza, Dan, Miller, John P., Vance, Jeffery M., Foroud, Tatiana, Beach, Thomas G., Myers, Richard H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386245/
https://ncbi.nlm.nih.gov/pubmed/22761592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002794
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