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Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate FOXO1 and Genes under Its Transcriptional Regulation

Parkinson disease (PD) is a complex neurodegenerative disorder with largely unknown genetic mechanisms. While the degeneration of dopaminergic neurons in PD mainly takes place in the substantia nigra pars compacta (SN) region, other brain areas, including the prefrontal cortex, develop Lewy bodies,...

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Bibliografiska uppgifter
Huvudupphovsmän: Dumitriu, Alexandra, Latourelle, Jeanne C., Hadzi, Tiffany C., Pankratz, Nathan, Garza, Dan, Miller, John P., Vance, Jeffery M., Foroud, Tatiana, Beach, Thomas G., Myers, Richard H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386245/
https://ncbi.nlm.nih.gov/pubmed/22761592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002794
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