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Fuzzy Tandem Repeats Containing p53 Response Elements May Define Species-Specific p53 Target Genes
Evolutionary forces that shape regulatory networks remain poorly understood. In mammals, the Rb pathway is a classic example of species-specific gene regulation, as a germline mutation in one Rb allele promotes retinoblastoma in humans, but not in mice. Here we show that p53 transactivates the Retin...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386156/ https://ncbi.nlm.nih.gov/pubmed/22761580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002731 |
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