Population Pharmacokinetics and Pharmacodynamics of Ribavirin in Patients with Chronic Hepatitis C Genotype 1 Infection

We report a population pharmacokinetic (PK) and pharmacodynamic (PD) model of orally administered ribavirin in patients with chronic hepatitis C virus (HCV) infection enrolled in a multicenter clinical trial, including the estimation of covariate effects on ribavirin PK parameters and sustained vira...

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Bibliografske podrobnosti
Main Authors: Jin, Runyan, Fossler, Michael J., McHutchison, John G., Howell, Charles D., Dowling, Thomas C.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385833/
https://ncbi.nlm.nih.gov/pubmed/22639111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9368-z
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