Optimum Ribavirin Exposure Overcomes Racial Disparity in Efficacy of Peginterferon and Ribavirin Treatment for Hepatitis C Genotype 1

OBJECTIVES: Peginterferon and ribavirin treatment is less effective for hepatitis C virus (HCV) genotype 1 infections in African Americans (AA) compared with Caucasian Americans (CA). Host genetic variability near the interleukin-28B (IL28B) gene locus is partly responsible. We investigated the rela...

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Detalhes bibliográficos
Main Authors: Jin, Runyan, Cai, Ling, Tan, Ming, McHutchison, John G., Dowling, Thomas C., Howell, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718255/
https://ncbi.nlm.nih.gov/pubmed/23090351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2012.306
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