Effects of IGF-1 on I(K) and I(K1) Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes

Previous studies suggest that sarcolemmal potassium currents play important roles in cardiac hypertrophy. IGF-1 contributes to cardiac hypertrophy via activation of PI3K/Akt signaling. However, the relationships between IGF-1, PI3K/Akt signaling and sarcolemmal potassium currents remain unknown. The...

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Hlavní autoři: Millis, Richard M., Alvin, Zikiar V., Zhao, Aiqiu, Haddad, Georges E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385609/
https://ncbi.nlm.nih.gov/pubmed/22761619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/712153
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