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Basal and IGF-I-dependent regulation of potassium channels by MAP kinases and PI3-kinase during eccentric cardiac hypertrophy

The potassium channels I(K) and I(K1), responsible for the action potential repolarization and resting potential respectively, are altered during cardiac hypertrophy. The activation of insulin-like growth factor-I (IGF-I) during hypertrophy may affect channel activity. The aim was to examine the mod...

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Autores principales: Teos, Leyla Y., Zhao, Aiqiu, Alvin, Zikiar, Laurence, Graham G., Li, Chuanfu, Haddad, Georges E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614587/
https://ncbi.nlm.nih.gov/pubmed/18757484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.321.2008
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