Spatiotemporal Dysfunction of the Vascular Permeability Barrier in Transgenic Mice with Sickle Cell Disease

Sickle cell disease (SCD) is characterized by chronic intravascular hemolysis that generates excess cell-free hemoglobin in the blood circulation. Hemoglobin causes multiple endothelial dysfunctions including increased vascular permeability, impaired reactivity to vasoactive agonists, and increased...

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Hlavní autoři: Ghosh, Samit, Tan, Fang, Ofori-Acquah, Solomon F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384933/
https://ncbi.nlm.nih.gov/pubmed/22778926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/582018
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