The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis

Rac1b, an alternative splice form of Rac1, has been previously shown to be upregulated in colon and breast cancer cells, suggesting an oncogenic role for Rac1b in these cancers. Our analysis of NSCLC tumor and matched normal tissue samples indicates Rac1b is upregulated in a significant fraction of...

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Autors principals: Zhou, Chun, Licciulli, Silvia, Avila, Jacqueline L., Cho, Miyoung, Troutman, Scott, Jiang, Ping, Kossenkov, Andrew, Showe, Louise C., Liu, Qin, Vachani, Anil, Albelda, Steven M., Kissil, Joseph L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384754/
https://ncbi.nlm.nih.gov/pubmed/22430205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.99
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