Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma

K-ras is the most commonly mutated oncogene in pancreatic cancer and its activation in murine models is sufficient to recapitulate the spectrum of lesions seen in human pancreatic ductal adenocarcinoma (PDAC). Recent studies suggest that Notch receptor signaling becomes reactivated in a subset of PD...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Hanlon, Linda, Avila, Jacqueline L., Demarest, Renée M., Troutman, Scott, Allen, Megan, Ratti, Francesca, Rustgi, Anil K., Stanger, Ben Z., Radtke, Fred, Adsay, Volkan, Long, Fenella, Capobianco, Anthony J., Kissil, Joseph L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880196/
https://ncbi.nlm.nih.gov/pubmed/20484026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4645
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items