Reactive oxygen species (ROS) by p66Shc longevity protein mediate non-genomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells

Steroid hormones exhibit diverse biological activities. Despite intensive studies on steroid function at the genomic level, their non-genomic action remains an enigma. In this study, we investigated the role of reactive oxygen species (ROS) in androgen-stimulated prostate cancer (PCa) cell prolifera...

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Detalhes bibliográficos
Main Authors: Veeramani, Suresh, Chou, Yu-Wei, Lin, Frank C., Muniyan, Sakthivel, Lin, Fen-Fen, Kumar, Satyendra, Xie, Yan, Lele, Subodh M, Tu, Yaping, Lina, Ming-Fong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384717/
https://ncbi.nlm.nih.gov/pubmed/22561705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.03.024
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