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Glucocorticoid and Estrogen Receptors Are Reduced in Mitochondria of Lung Epithelial Cells in Asthma

Mitochondrial glucocorticoid (mtGR) and estrogen (mtER) receptors participate in the coordination of the cell’s energy requirement and in the mitochondrial oxidative phosphorylation enzyme (OXPHOS) biosynthesis, affecting reactive oxygen species (ROS) generation and induction of apoptosis. Although...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Simoes, Davina C. M., Psarra, Anna-Maria G., Mauad, Thais, Pantou, Ioanna, Roussos, Charis, Sekeris, Constantine E., Gratziou, Christina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384641/
https://ncbi.nlm.nih.gov/pubmed/22761735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039183
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