Glucocorticoid and Estrogen Receptors Are Reduced in Mitochondria of Lung Epithelial Cells in Asthma

Mitochondrial glucocorticoid (mtGR) and estrogen (mtER) receptors participate in the coordination of the cell’s energy requirement and in the mitochondrial oxidative phosphorylation enzyme (OXPHOS) biosynthesis, affecting reactive oxygen species (ROS) generation and induction of apoptosis. Although...

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Main Authors: Simoes, Davina C. M., Psarra, Anna-Maria G., Mauad, Thais, Pantou, Ioanna, Roussos, Charis, Sekeris, Constantine E., Gratziou, Christina
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384641/
https://ncbi.nlm.nih.gov/pubmed/22761735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039183
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