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HP1a Targets the Drosophila KDM4A Demethylase to a Subset of Heterochromatic Genes to Regulate H3K36me3 Levels

The KDM4 subfamily of JmjC domain-containing demethylases mediates demethylation of histone H3K36me3/me2 and H3K9me3/me2. Several studies have shown that human and yeast KDM4 proteins bind to specific gene promoters and regulate gene expression. However, the genome-wide distribution of KDM4 proteins...

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Detalhes bibliográficos
Main Authors: Lin, Chia-Hui, Paulson, Ariel, Abmayr, Susan M., Workman, Jerry L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384587/
https://ncbi.nlm.nih.gov/pubmed/22761891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039758
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