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Pathogenesis-related mutations in the T-loops of human mitochondrial tRNAs affect 3′ end processing and tRNA structure

Numerous mutations in the mitochondrial genome are associated with maternally transmitted diseases and syndromes that affect muscle and other high energy-demand tissues. The mitochondrial genome encodes 13 polypeptides, 2 rRNAs and 22 interspersed tRNAs via long bidirectional polycistronic primary t...

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Sonraí Bibleagrafaíochta
Main Authors: Levinger, Louis, Serjanov, Dmitri
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384583/
https://ncbi.nlm.nih.gov/pubmed/22336717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.19025
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