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Mitochondrial tRNA 3′ end metabolism and human disease
Over 150 mutations in the mitochondrial genome have been shown to be associated with human disease. Remarkably, two-thirds of them are found in tRNA genes, which constitute only one-tenth of the mitochondrial genome. A total of 22 tRNAs punctuate the genome and are produced together with 11 mRNAs an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524294/ https://ncbi.nlm.nih.gov/pubmed/15477393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh884 |
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