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Arp2/3 complex–dependent actin networks constrain myosin II function in driving retrograde actin flow
The Arp2/3 complex nucleates actin filaments to generate networks at the leading edge of motile cells. Nonmuscle myosin II produces contractile forces involved in driving actin network translocation. We inhibited the Arp2/3 complex and/or myosin II with small molecules to investigate their respectiv...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384413/ https://ncbi.nlm.nih.gov/pubmed/22711700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111052 |
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