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Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT–dependent neurite outgrowth in Aplysia bag cell neurons

Neurite outgrowth in response to soluble growth factors often involves changes in intracellular Ca(2+); however, mechanistic roles for Ca(2+) in controlling the underlying dynamic cytoskeletal processes have remained enigmatic. Bag cell neurons exposed to serotonin (5-hydroxytryptamine [5-HT]) respo...

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書誌詳細
主要な著者: Zhang, Xiao-Feng, Hyland, Callen, Van Goor, David, Forscher, Paul
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521690/
https://ncbi.nlm.nih.gov/pubmed/23097492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-10-0715
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