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The role of the excision-repair enzymes in mutation-induction by cis-Pt(NH3)2Cl2.

Mutation induction by cis-Pt(NH3)2Cl2 (cisplatin) has been shown to be absent in E.coli strains carrying a deletion of the uvrB gene (1). This suggested that excision-repair, which is normally thought to be error-free, is involved in mutation induction with cisplatin. Here, the role of the excision...

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Bibliographic Details
Main Authors: Brouwer, J, Vollebregt, L, van de Putte, P
Format: Artigo
Language:Inglês
Published: 1988
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC338436/
https://ncbi.nlm.nih.gov/pubmed/3045762
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