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Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2
Enzymes that modify the epigenetic status of cells provide attractive targets for therapy in various diseases. The therapeutic development of epigenetic modulators, however, has been largely limited to direct targeting of catalytic active site conserved across multiple members of an enzyme family, w...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384312/ https://ncbi.nlm.nih.gov/pubmed/22396528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks189 |
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