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Notch controls the magnitude of T helper cell responses by promoting cellular longevity
Generation of effective immune responses requires expansion of rare antigen-specific CD4(+) T cells. The magnitude of the responding population is ultimately determined by proliferation and survival. Both processes are tightly controlled to limit responses to innocuous antigens. Sustained expansion...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384214/ https://ncbi.nlm.nih.gov/pubmed/22615412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206044109 |
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