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MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length

Dendritic cells (DCs) and B cells present antigen-derived peptides bound to MHC class II (MHC II) molecules for recognition by CD4-positive T lymphocytes. DCs control the intracellular traffic of peptide–MHC II complexes by regulating the ubiquitination of MHC II. In resting or “immature” DCs, ubiqu...

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Detalhes bibliográficos
Main Authors: Ma, Jessica K., Platt, Mia Y., Eastham-Anderson, Jeffrey, Shin, Jeoung-Sook, Mellman, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384207/
https://ncbi.nlm.nih.gov/pubmed/22566640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202977109
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