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Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling
Toll-like receptor (TLR) 3 is an endosomal TLR that mediates immune responses against viral infections upon activation by its ligand double-stranded RNA, a replication intermediate of most viruses. TLR3 is expressed widely in the body and activates both the innate and adaptive immune systems. Howeve...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384196/ https://ncbi.nlm.nih.gov/pubmed/22611194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115091109 |
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