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Cathepsin B cleavage of the trypsinogen activation peptide

BACKGROUND: Cathepsin B is thought to play a central role in intrapancreatic trypsinogen activation and the onset of pancreatitis. A recent investigation of the cathepsin B mediated activability of wildtype trypsinogen and their mutations N29I, N29T and R122H, which are associated to hereditary panc...

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Autors principals: Teich, Niels, Bödeker, Hans, Keim, Volker
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC117221/
https://ncbi.nlm.nih.gov/pubmed/12102727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-2-16
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