Oncogene-mediated alterations in chromatin conformation

Emerging evidence suggests that chromatin adopts a nonrandom 3D topology and that the organization of genes into structural hubs and domains affects their transcriptional status. How chromatin conformation changes in diseases such as cancer is poorly understood. Moreover, how oncogenic transcription...

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Hauptverfasser: Rickman, David S., Soong, T. David, Moss, Benjamin, Mosquera, Juan Miguel, Dlabal, Jan, Terry, Stéphane, MacDonald, Theresa Y., Tripodi, Joseph, Bunting, Karen, Najfeld, Vesna, Demichelis, Francesca, Melnick, Ari M., Elemento, Olivier, Rubin, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384175/
https://ncbi.nlm.nih.gov/pubmed/22615383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112570109
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