Oncogene-mediated alterations in chromatin conformation

Emerging evidence suggests that chromatin adopts a nonrandom 3D topology and that the organization of genes into structural hubs and domains affects their transcriptional status. How chromatin conformation changes in diseases such as cancer is poorly understood. Moreover, how oncogenic transcription...

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Bibliografiske detaljer
Main Authors: Rickman, David S., Soong, T. David, Moss, Benjamin, Mosquera, Juan Miguel, Dlabal, Jan, Terry, Stéphane, MacDonald, Theresa Y., Tripodi, Joseph, Bunting, Karen, Najfeld, Vesna, Demichelis, Francesca, Melnick, Ari M., Elemento, Olivier, Rubin, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384175/
https://ncbi.nlm.nih.gov/pubmed/22615383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112570109
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