Oncogene-mediated alterations in chromatin conformation

Emerging evidence suggests that chromatin adopts a nonrandom 3D topology and that the organization of genes into structural hubs and domains affects their transcriptional status. How chromatin conformation changes in diseases such as cancer is poorly understood. Moreover, how oncogenic transcription...

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Detalhes bibliográficos
Main Authors: Rickman, David S., Soong, T. David, Moss, Benjamin, Mosquera, Juan Miguel, Dlabal, Jan, Terry, Stéphane, MacDonald, Theresa Y., Tripodi, Joseph, Bunting, Karen, Najfeld, Vesna, Demichelis, Francesca, Melnick, Ari M., Elemento, Olivier, Rubin, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384175/
https://ncbi.nlm.nih.gov/pubmed/22615383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112570109
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