Rab14 and Its Exchange Factor FAM116 Link Endocytic Recycling and Adherens Junction Stability in Migrating Cells

Rab GTPases define the vesicle trafficking pathways underpinning cell polarization and migration. Here, we find that Rab4, Rab11, and Rab14 and the candidate Rab GDP-GTP exchange factors (GEFs) FAM116A and AVL9 are required for cell migration. Rab14 and its GEF FAM116A localize to and act on an inte...

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Bibliographic Details
Main Authors: Linford, Andrea, Yoshimura, Shin-ichiro, Bastos, Ricardo Nunes, Langemeyer, Lars, Gerondopoulos, Andreas, Rigden, Daniel J., Barr, Francis A.
Format: Artigo
Language:Inglês
Published: Cell Press 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383995/
https://ncbi.nlm.nih.gov/pubmed/22595670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.04.010
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