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Upregulation of Cycolooxygenase-2 (COX-2) and Microsomal Prostaglandin E(2) Synthase-1 (mPGES-1) in Wall of Ruptured Human Cerebral Aneurysms: Preliminary Results

BACKGROUND AND PURPOSE: Cyclooxygenase-2 (COX-2) and Microsomal Prostaglandin E(2) Synthase-1 (mPGES-1) catalyze isomerization of the cyclooxygenase product PGH(2) into PGE(2). Deletion of COX-2/mPGES-1 suppresses carotid artery atherogenesis, angiotensin II-induced aortic aneurysms formation, and a...

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Detalhes bibliográficos
Main Authors: Hasan, David, Hashimoto, Tomoki, Kung, David, Macdonald, R. Loch, Winn, H. Richard, Heistad, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383865/
https://ncbi.nlm.nih.gov/pubmed/22588264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.112.655829
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