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Optical control of endogenous proteins with a photo-switchable conditional subunit reveals a role for TREK1 in GABAB signaling
Selective ligands are lacking for many neuronal signaling proteins. Photoswitched tethered ligands (PTLs) have enabled fast and reversible control of specific proteins containing a PTL anchoring site and have been used to remote control over-expressed proteins. We report here a novel scheme for opti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383668/ https://ncbi.nlm.nih.gov/pubmed/22726831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.04.026 |
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