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Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis
Fidgetin is a member of the AAA protein superfamily with important roles in mammalian development. Here we show that human Fidgetin is a potent microtubule severing and depolymerizing the enzyme used to regulate mitotic spindle architecture, dynamics and anaphase A. In vitro, recombinant human Fidge...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383595/ https://ncbi.nlm.nih.gov/pubmed/22672901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20849 |
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