Motor domain phosphorylation and regulation of the Drosophila kinesin 13, KLP10A

Microtubule (MT)-destabilizing kinesin 13s perform fundamental roles throughout the cell cycle. In this study, we show that the Drosophila melanogaster kinesin 13, KLP10A, is phosphorylated in vivo at a conserved serine (S573) positioned within the α-helix 5 of the motor domain. In vitro, a phosphom...

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Hlavní autoři: Mennella, Vito, Tan, Dong-Yan, Buster, Daniel W., Asenjo, Ana B., Rath, Uttama, Ma, Ao, Sosa, Hernando J., Sharp, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733746/
https://ncbi.nlm.nih.gov/pubmed/19687256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902113
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