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Do human transposable element small RNAs serve primarily as genome defenders or genome regulators?
It is currently thought that small RNA (sRNA) based repression mechanisms are primarily employed to mitigate the mutagenic threat posed by the activity of transposable elements (TEs). This can be achieved by the sRNA guided processing of TE transcripts via Dicer-dependent (e.g., siRNA) or Dicer-inde...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383446/ https://ncbi.nlm.nih.gov/pubmed/22754749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.19031 |
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