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Do human transposable element small RNAs serve primarily as genome defenders or genome regulators?

It is currently thought that small RNA (sRNA) based repression mechanisms are primarily employed to mitigate the mutagenic threat posed by the activity of transposable elements (TEs). This can be achieved by the sRNA guided processing of TE transcripts via Dicer-dependent (e.g., siRNA) or Dicer-inde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Kevin J., Conley, Andrew B., Lunyak, Victoria V., Jordan, I. King
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383446/
https://ncbi.nlm.nih.gov/pubmed/22754749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.19031
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