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Do human transposable element small RNAs serve primarily as genome defenders or genome regulators?

It is currently thought that small RNA (sRNA) based repression mechanisms are primarily employed to mitigate the mutagenic threat posed by the activity of transposable elements (TEs). This can be achieved by the sRNA guided processing of TE transcripts via Dicer-dependent (e.g., siRNA) or Dicer-inde...

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Detalhes bibliográficos
Main Authors: Lee, Kevin J., Conley, Andrew B., Lunyak, Victoria V., Jordan, I. King
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383446/
https://ncbi.nlm.nih.gov/pubmed/22754749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.19031
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