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Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3' UTRs and Near Stop Codons

Methylation of the N6 position of adenosine (m6A) is a post-transcriptional modification of RNA whose prevalence and physiological relevance is poorly understood. The recent discovery that FTO, an obesity risk gene, encodes an m6A demethylase implicates m6A as an important regulator of physiological...

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Detalhes bibliográficos
Main Authors: Meyer, Kate D., Saletore, Yogesh, Zumbo, Paul, Elemento, Olivier, Mason, Christopher E., Jaffrey, Samie R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383396/
https://ncbi.nlm.nih.gov/pubmed/22608085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.003
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