VIRMA mediates preferential m(6)A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

N(6)-methyladenosine (m(6)A) is enriched in 3′untranslated region (3′UTR) and near stop codon of mature polyadenylated mRNAs in mammalian systems and has regulatory roles in eukaryotic mRNA transcriptome switch. Significantly, the mechanism for this modification preference remains unknown, however....

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Publicado no:Cell Discov
Main Authors: Yue, Yanan, Liu, Jun, Cui, Xiaolong, Cao, Jie, Luo, Guanzheng, Zhang, Zezhou, Cheng, Tao, Gao, Minsong, Shu, Xiao, Ma, Honghui, Wang, Fengqin, Wang, Xinxia, Shen, Bin, Wang, Yizhen, Feng, Xinhua, He, Chuan, Liu, Jianzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826926/
https://ncbi.nlm.nih.gov/pubmed/29507755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0019-0
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